This enemy is literally a stronger version of Mist Grove 1's White Roundhead Mushroom. Although they are significantly stronger and lack a Fire weakness, they suffer from the exact same issues as that enemy, so similar strategies from them can just as easily apply here. Be mindful of the Copters hovering around, however, as they will cause more damage than this enemy can. Also, getting close to the mushrooms, in certain screens, can set your characters up to be attacked by Orange Roundhead Trees. Fire type weapons such as the Magician's Lava 6 are best against this enemy, especially from a far range.